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Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus

โœ Scribed by Philip Roelandt; Susan Obeid; Jan Paeshuyse; Jolien Vanhove; Alfons Van Lommel; Yaakov Nahmias; Frederik Nevens; Johan Neyts; Catherine M Verfaillie


Book ID
116652776
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
909 KB
Volume
57
Category
Article
ISSN
0168-8278

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CD56 ุ‰ T cells are abundant in liver and play an important role in defense against viral infections. However, the role of CD56 ุ‰ T cells in control of hepatitis C virus (HCV) infection remains to be determined. We investigated the noncytolytic anti-HCV activity of primary CD56 ุ‰ T cells in human hep