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Human pharmacokinetic profile of 1,25-dihydroxyvitamin D3-glycoside of herbal origin

✍ Scribed by Mathis, G.A.; Toggenburger, A.; Pokorny, R.; Autzen, S.; Ibanez, R.; Romeis, P.; Bachmann, H.

Book ID: 123073078
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 386 KB
Volume: 144
Category: Article
ISSN: 0960-0760
DOI: 10.1016/j.jsbmb.2013.11.016

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## Background: Although topical 1,25-dihydroxyvitamin d3 (calcitriol, 1, 25(oh)2d3) and its analogues, calcipotriol and tacalcitol, are effective for patients with psoriasis, some patients show little or no response. there is a need to develop more potent analogues of 1, 25(oh)2d3. hexafluoro-1,25(