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Human Peroxisomal 3-oxoacyl-coenzyme A Thiolase Deficiency

✍ Scribed by André W. Schram, Sidney Goldfischer, Carlo W. T. Van Roermund, Elisabeth M. Brouwer-Kelder, Janna Collins, Takashi Hashimoto, Hugo S. A. Heymans, Henk Van Den Bosch, Ruud B. H. Schutgens, Joseph M. Tager and Ronald J. A. Wanders

Book ID
123634318
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
654 KB
Volume
84
Category
Article
ISSN
0027-8424

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📜 SIMILAR VOLUMES

An acyl-coenzyme a chain length dependen
An acyl-coenzyme a chain length dependent assay for 3-oxoacyl-coenzyme a thiolases employing acetyldithio-coenzyme A
✍ Louise V. Wrensford; Chris Coppola; Vernon E. Abderson 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 640 KB

An assay for 3-oxoacyl-coenzyme A (3-oxoacyl-CoA) thiolases is described. The reaction utilizes acetyldithio-CoA as the nucleophile and variable chain length saturated acyl-CoA's as the electrophiles. The properties of the 3-oxoacyl-CoA dithioester product, notably a pKa of 6.6 +/- 0.1 and an extinc