𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions

✍ Scribed by Brooke E. Hoots; Joel M. Palefsky; Jeanne M. Pimenta; Jennifer S. Smith

Publisher
John Wiley and Sons
Year
2009
Tongue
French
Weight
194 KB
Volume
124
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A systematic review was conducted of HPV type distribution in anal cancer and anal high‐grade and low‐grade squamous intraepithelial lesions (HSIL and LSIL). A Medline search of studies using PCR or hybrid capture for HPV DNA detection was completed. A total of 1,824 cases were included: 992 invasive anal cancers, 472 HSIL cases and 360 LSIL cases. Crude HPV prevalence in anal cancer, HSIL, and LSIL was 71, 91 and 88%, respectively. HPV16/18 prevalence was 72% in invasive anal cancer, 69% in HSIL and 27% in LSIL. The HPV 16 and/or 18 prevalence in invasive anal cancer cases was similar to that reported in invasive cervical cancer. If ongoing clinical trials show efficacy in preventing anal HPV infection and associated anal lesions, prophylactic HPV vaccines may play an important role for the primary prevention of these cancers in both genders. Β© 2008 Wiley‐Liss, Inc.

πŸ“œ SIMILAR VOLUMES

Human papillomavirus genotype distributi
Human papillomavirus genotype distribution in anal cancer in France: The EDiTH V study
✍ Laurent Abramowitz; Anne-Carole Jacquard; Fatiha Jaroud; Julie Haesebaert; Laure πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 207 KB πŸ‘ 1 views

## Abstract Anal cancer is a rare cancer but its incidence is increasing. Human papillomavirus (HPV) infection seems to be associated with the occurrence of most cases. The genotype‐specific prevalence of HPV in anal cancer was estimated to assess the potential benefit of HPV vaccination in France.

Trends in incidence of anal cancer and h
Trends in incidence of anal cancer and high-grade anal intraepithelial neoplasia in Denmark, 1978–2008
✍ Ann Nielsen; Christian Munk; Susanne K. Kjaer πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 French βš– 292 KB

## Abstract The aim of the study was to determine the incidences of anal cancer and high‐grade anal intraepithelial neoplasia (AIN2/3) over time in Danish women and men. Describing the burden of anal cancer and AIN may be valuable in future evaluations of the human papillomavirus (HPV) vaccine. We

Comparison of human papillomavirus distr
Comparison of human papillomavirus distribution in cytologic subgroups of low-grade squamous intraepithelial lesion
✍ Zuna, Rosemary E. ;Wang, Sophia S. ;Schiffman, Mark ;Solomon, Diane πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 163 KB

## Background: Low-grade squamous intraepithelial lesion (lsil) subsumes the formerly delineated cytologic categories of human papillomavirus (hpv)-associated cell changes (koilocytotic atypia) and low-grade dysplasia/cervical intraepithelial neoplasia (cin) grade 1 (cin1). in this study, the objec