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Human papillomavirus type 17 transcripts expressed in skin carcinoma tissue of a patient with epidermodysplasia verruciformis

✍ Scribed by Masuo Yutsudo; Akira Hakura

Publisher: John Wiley and Sons
Year: 1987
Tongue: French
Weight: 585 KB
Volume: 39
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910390507

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✦ Synopsis

Certain types of human papillomavirus (HPV) are involved in skin carcinogenesis in epiderrnodysplasia verruciformis. However, no gene or gene product of HPV associated with skin carcinogenesis has yet been identified. Here, we report HPV-17 transcripts expressed in skin carcinoma tissue of an epidermodysplasia verruciformis patient infected with HPV-17. Further, we show that one of these transcripts was localized to a portion of the genome which contains the 3' open reading frames of the early region (E2, E3, E4 and E5). The analogous region in bovine papillomavirus type I has been shown to contain a transforming gene (Nakabayashi et a/.,

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Distinctive distribution of human papillomavirus type 16 and type 20 DNA in the tonsillar and the skin carcinomas of a patient with epidermodysplasia verruciformis

✍ T. Ishiji; M. Kawase; M. Honda; M. Niimura; E. Yoshimura; T. Sata; T. Matsukura 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 549 KB

## Background: Epidermodysplasia verruciformis (ev) is a rare skin disease characterized by disseminated pityriasis versicolor-like or flat wart-like lesions and by the development of skin carcinomas. it is well established that specific cutaneous human papillomaviruses (ev-hpvs) are associated wit