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Human Papillomavirus Type 16 Cooperates with Activated ras and fos Oncogenes in the Hormone-Dependent Transformation of Primary Mouse Cells

โœ Scribed by T. Crook, A. Storey, N. Almond, K. Osborn and L. Crawford


Book ID
123636319
Publisher
National Academy of Sciences
Year
1988
Tongue
English
Weight
923 KB
Volume
85
Category
Article
ISSN
0027-8424

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Transformation of baby mouse kidney epithelial cells by human papillomavirus (HPV) type 16 is dependent both upon the cooperating oncogene and on the hormonal conditions after transfection. With v-fos as the oncogene, the transformed cells require glucocorticoid hormone, such as dexamethasone, for p