Human papillomavirus DNA in distant metastases of cervical cancer
β Scribed by H. Ikenberg; G. Teufel; B. Schmitt; F. Kommoss; B. Stanimirovic; A. Pfleiderer
- Book ID
- 118891573
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 139 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0020-7292
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π SIMILAR VOLUMES
Human papillomavirus (HPV) 16 is most prevalent in cenical cancers and also persists in metastases. We examined HPV 16-DNA-positive primary cancers and several lymph nodes from each of 14 patients to evaluate the use of HPV16 D N A as a diagnostic marker for the detection of early node involvement.
Human papillomavirus (HPV) type 16 DNA is frequent in invasive cervical cancers. Among 43 patients with invasive cervical cancer, HPV-16-positive tumors spread to the parametrial and pelvic lymph nodes significantly more often than did HPV-16-negative tumors ( P < 0.05). Demonstration of HPV-16 DNA