Human ovarian surface epithelial (OSE) cells express LH/hCG receptors, and HCG inhibits apoptosis of OSE cells via up-regulation of insulin-like growth factor-1

Human chorionic gonadotropin (hCG) inhib

Human chorionic gonadotropin (hCG) inhibits cisplatin-induced apoptosis in ovarian cancer cells: Possible role of up-regulation of insulin-like growth factor-1 by hCG

✍ Hideki Kuroda; Masaki Mandai; Ikuo Konishi; Yasuichiro Yura; Yuko Tsuruta; Atia 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 330 KB 👁 2 views

Gonadotropins have been suggested to play a role in the development or progression of ovarian cancer, and we have previously reported the expression of luteinizing hormone/ human chorionic gonadotropin (LH/hCG) receptor in 40% of epithelial ovarian carcinomas. To examine the biological effect of LH/