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Human organic cation transporter (OCT1andOCT2) gene polymorphisms and therapeutic effects of metformin

โœ Scribed by Eriko Shikata; Rei Yamamoto; Hiroshi Takane; Chiaki Shigemasa; Tadasu Ikeda; Kenji Otsubo; Ichiro Ieiri

Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
181 KB
Volume
52
Category
Article
ISSN
1435-232X

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โœ Yuki Kawasaki; Yukio Kato; Yoshimichi Sai; Akira Tsuji ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 139 KB ๐Ÿ‘ 1 views

The organic cation transporter OCTN1 (SLC22A4) is expressed ubiquitously, with strong expression in kidney, trachea, bone marrow, and fetal liver, and it mediates transport of organic cations in a pH-dependent manner. Recent studies have identified single nucleotide polymorphisms (SNPs) of OCTN1 in