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Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated aldehydes by phagocytes at sites of inflammation.

✍ Scribed by Anderson, M M; Hazen, S L; Hsu, F F; Heinecke, J W


Book ID
118006920
Publisher
American Society for Clinical Investigation
Year
1997
Tongue
English
Weight
224 KB
Volume
99
Category
Article
ISSN
0021-9738

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