𝔖 Bobbio Scriptorium
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Human mononuclear cells produce interferon in coculture with tumor cells

✍ Scribed by CROWLEY, N

Book ID
122047461
Publisher
Elsevier Science
Year
1981
Weight
111 KB
Volume
17
Category
Article
ISSN
0277-5379

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Nude mice were inoculated with CHOIIFN-y cells, a line of Chinese hamster ovary tumor cells, that had been genetically engineered to produce murine IFN-y. Severe cachexia, as evident from body weight loss and reduced food intake, occurred in these mice, but not in those injected with CHOI control ce