## Abstract The Editors welcome topical correspondence from readers relating to articles published in the Journal. Responses can be sent electronically via the BJS website (www.bjs.co.uk) or by post. All letters will be reviewed and, if approved, appear on the website. A selection of these will be
Human model of duodenogastro-oesophageal reflux in the development of Barrett's metaplasia
โ Scribed by S. M. Dresner; S. M. Griffin; J. Wayman; M. K. Bennett; N. Hayes; S. A. Raimes
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 192 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0007-1323
- DOI
- 10.1002/bjs.4169
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Villin is a cytoskeletal protein that is involved in the formation of brush-border microvilli in normal small intestine and colon epithelium. This protein is present in Barrett's metaplasia but is reported not to be expressed in Barrett's adenocarcinoma. In this study, we analyzed villin protein exp
## Abstract ## BACKGROUND The Pโglyprotein (Pโgp), which is a membrane channel encoded by the __MDR1__ gene, represents a possible explanation for multidrug resistance in human hepatoblastoma (HB). Pโgp shows upโregulation in tumor cells after chemotherapy; however, to date, its exact role in HB h