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Human mitochondrial glutamic-oxaloacetic-transaminase, GOTM: Formal genetics

✍ Scribed by H. Ritter; J. Kömpf

Publisher
Springer
Year
1979
Tongue
English
Weight
142 KB
Volume
51
Category
Article
ISSN
0340-6717

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✦ Synopsis

The polymorphism of human GOTM was investigated in red blood cells by means of routine starch gel electrophoresis. The formal model of two common alleles, GOTM1 and GOTM2, at an autosomal locus GOTM was confirmed by examination of 640 mother-child pairs. The frequency of GOTM1 in this sample from southwestern Germany was calculated to be 0.981 +/- 0.003.

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Glutamate oxaloacetic transaminase (L-aspertate: 2-oxoglutarate aminotransferase, E.C. 2.6.1.1; GOT) was found to occur in five distinct electrophoretic forms in different tissue extracts from a number of highly inbred strains of Zea mays L. No major qualitative differences were detected in the vari