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Human mitochondrial genome and the evolution of methionine transfer ribonucleic acids

✍ Scribed by Raik Mikelsaar

Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
555 KB
Volume
105
Category
Article
ISSN
0022-5193

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✦ Synopsis

The recently deciphered sequence of the human mitochondrial genome is analyzed in the light of an archigenetic hypothesis, according to which mitochondria are derived neither from pro-nor eukaryotes but from more primitive organisms. The possibility that animal mitochondria have only one gene both for elongator and initiator methionine tRNA is supported but C-A pair forming cytosine in the anticodon of these tRNAs is considered to be unmodified. The evolution of the gene and of the codon reading pattern of methionine tRNA is discussed.

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