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Human mitochondrial complex I assembly is mediated by NDUFAF1

✍ Scribed by Rutger O. Vogel; Rolf J. R. J. Janssen; Cristina Ugalde; Melissa Grovenstein; Richard J Huijbens; Henk-Jan Visch; Lambert P. van den Heuvel; Peter H. Willems; Massimo Zeviani; Jan A. M. Smeitink; Leo G. J. Nijtmans

Book ID
111310226
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
370 KB
Volume
272
Category
Article
ISSN
1432-1327

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## Abstract NADH‐ubiquinone oxidoreductase (complex I) is a large, multimeric enzyme complex involved in the generation of ATP by oxidative phosphorylation. Complex I is comprised of 45 subunits which must be assembled together in a coordinated process to form the mature holoenzyme. In recent years