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Human mesenchymal stem cell culture: rapid and efficient isolation and expansion in a defined serum-free medium

✍ Scribed by Sunghoon Jung; Arindom Sen; Lawrence Rosenberg; Leo A. Behie

Book ID: 112219747
Publisher: Wiley (John Wiley & Sons)
Year: 2011
Tongue: English
Weight: 657 KB
Volume: 6
Category: Article
ISSN: 1932-6254
DOI: 10.1002/term.441

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## Abstract Human bone marrow mesenchymal stromal cells (hMSC) are currently investigated for a variety of therapeutic applications. However, most expansion protocols still use fetal calf serum (FCS) as growth factor supplement which is a potential source of undesired xenogeneic pathogens. We estab