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Human melanomas express functional P2X7receptors

✍ Scribed by Nicholas White; Peter E. M. Butler; Geoffrey Burnstock

Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
276 KB
Volume
321
Category
Article
ISSN
0302-766X

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Flow cytometric analysis reveals that 5 human melanoma cell lines (M 14, IGR3, ME1477, JUSO, GLLI9) express both aand P chain of the interleukin 2 receptor (IL-2Ra and IL-2Rp). These chains are able to specifically bind IL-2 and to form high-affinity heterodimers (IL-2RaP). Analysis of poly At RNAs