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Human MAIT and CD8 cells develop from a pool of type-17 precommitted CD8+ T cells

✍ Scribed by Walker, L. J.; Kang, Y.-H.; Smith, M. O.; Tharmalingham, H.; Ramamurthy, N.; Fleming, V. M.; Sahgal, N.; Leslie, A.; Oo, Y.; Geremia, A.; Scriba, T. J.; Hanekom, W. A.; Lauer, G. M.; Lantz, O.; Adams, D. H.; Powrie, F.; Barnes, E.; Klenerman, P.


Book ID
118176874
Publisher
American Society of Hematology
Year
2012
Tongue
English
Weight
938 KB
Volume
119
Category
Article
ISSN
0006-4971

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## Background: We have previously established tumour t-cell lines, both from the skin and from the blood of patients with a cutaneous t-cell lymphoma (ctcl). in one patient, the tumour cells and the derived cell lines had a cd3+ cd4+ cd8- phenotype and a trisomy of chromosome 7. they expressed thre