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Human lung tumour cell line adapted to grow in serum-free medium secretes angiogenesis factor

✍ Scribed by S. Kumar; D. West; Mary Daniel; Anne Hancock; T. Carr


Publisher
John Wiley and Sons
Year
1983
Tongue
French
Weight
490 KB
Volume
32
Category
Article
ISSN
0020-7136

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✦ Synopsis


Abstract

A human lung tumour cell line has been grown in serum‐free medium for 12 months and during this period cells were subcultured every 4 days. The culture medium contained an angiogenesis factor which has been purified and shown to be similar to that isolated from other sources including solid tumours. This is the first report that demonstrates de novo synthesis and secretion of angiogenesis factor by a cell line adapted to grow in a serum‐free medium.