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Human L1 Retrotransposition Is Associated with Genetic Instability In Vivo

✍ Scribed by David E. Symer; Carla Connelly; Suzanne T. Szak; Emerita M. Caputo; Gregory J. Cost; Giovanni Parmigiani; Jef D. Boeke


Book ID
117269218
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
348 KB
Volume
110
Category
Article
ISSN
0092-8674

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## Abstract Lack of hormone dependency in prostate cancers is an irreversible event that occurs through generation of genomic instability induced by androgen deprivation. Indeed, the cytogenetic profile of hormone‐dependent (HD) prostate cancer remains stable as long as it received a hormone supply