Human Interleukin for DA Cells/Leukemia Inhibitory Factor and Oncostatin M Enhance Membrane Expression of Intercellular Adhesion Molecule-1 on Melanoma Cells but not the Shedding of its Soluble Form

Upmodulation of αvβ1 integrin expression

Upmodulation of αvβ1 integrin expression on human tumor cells by human interleukin for DA cells/leukemia inhibitory factor and oncostatin M: Correlation with increased cell adhesion on fibronectin

✍ Dominique Heymann; Jean Harb; Sophie Ringeard; Fréadéric Blanchard; Danielle Las 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 972 KB

## Abstract Integrins belong to a large family of heterodimeric membrane glycoproteins which mediate cell‐cell or cell‐extracellular matrix interactions. These interactions could play a major role during the migration of tumor cells across the extracellular matrix and vascular endothelium and would