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Human Immunoglobulin Light Chains λ Form Amyloid Fibrils and Granular Aggregates in Solution

✍ Scribed by O. P. Bliznyukov; L. D. Kozmin; L. L. Vysotskaya; A. K. Golenkov; V. M. Tishchenko; M. P. Samoylovich; V. B. Klimovich


Book ID
106372739
Publisher
Springer
Year
2005
Tongue
English
Weight
612 KB
Volume
70
Category
Article
ISSN
0006-2979

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## Background: Systemic amyloidosis occurs as a result of amyloid deposition in various tissues. the amyloid fibrils in systemic amyloidosis have been reported to originate from immunoglobulin light chains. ## Objective: We studied the composition of amyloid fibrils from two patients with plasma