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Human Immunoglobulin Isotype Switching : Studies at the DNA Level

✍ Scribed by E. E. MAX; F. C. MILLS; N. HARINDRANATH

Book ID
119872556
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
742 KB
Volume
764
Category
Article
ISSN
0890-6564

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## Abstract Immunofluorescent techniques were used to examine several aspects of B cell ontogeny in humans. Large lymphoid cells containing intracytoplasmic IgM (pre‐B cells) were present in fetal liver as early as 7 weeks of gestation, approximately 2 weeks prior to the appearance of surface IgM p