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Human immunoglobulin G reduces the pathogenicity of aquaporin-4 autoantibodies in neuromyelitis optica

✍ Scribed by Ratelade, Julien; Smith, Alex J.; Verkman, A.S.

Book ID: 121712582
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 659 KB
Volume: 255
Category: Article
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2014.03.004

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## Abstract ## Background Genetic manipulation of the allograft is an attractive approach to prevent the graft against chronic deterioration through stable expression of immunomodulatory or protective genes. However, the best strategy for prevention of chronic allograft deterioration remains uncle