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Human immunodeficiency virus type 1-anchored CD40 ligand induces secretion of the chemokine interleukin-8 by human primary macrophages

✍ Scribed by Émilie Maurais; Réjean Cantin; Michel J. Tremblay

Book ID
113947712
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
674 KB
Volume
385
Category
Article
ISSN
0042-6822

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## Abstract CXCL8 is a CXC chemokine that recruits leukocytes to sites of inflammation. Expression of CXCL8 in the CNS has been demonstrated in neuroinflammatory diseases, including human immunodeficiency virus (HIV‐1) encephalitis, but the mechanism of secretion of this chemokine is not fully unde