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Human Immune Reconstitution With Spleen Cells in SCID/Beige Mice

✍ Scribed by B. Marcheix; H. Yacoub-Youssef; D. Calise; J.-C. Thiers; H. Benoist; N. Blaes; B. Ségui; M. Thomsen; C. Dambrin

Book ID
116931314
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
53 KB
Volume
37
Category
Article
ISSN
0041-1345

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## Abstract Immunocompromised mouse models have been extensively used to assess human cell implantation for evaluation of cytotherapy, gene therapy and tissue engineering strategies, as these mice are deficient in T and B lymphoid cells. However, the innate immune response and its effect on human c