HUMAN IgG3 ALLOTYPES, WITH SPECIAL REFERENCE TO A NEW ALLOTYPE RELATED TO G3m(g) (G3m21)
โ Scribed by Loghem, Erna van ;Blanc, Madeleine ;Lange, Gerda De
- Book ID
- 114830369
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 607 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0960-7420
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The human G1m1 allotype comprises two amino acids, D12 and L14, in the CH3 domain of IGHG1. Although the G1m1 allotype is prevalent in human populations, โผ40% of Caucasiods are homozygous for the nG1m1 allotype corresponding to E12 and M14. Peptides derived from the G1m1 region were tested for their
## Abstract In this paper we report the structural basis for the nonexpression of G1m(3) and Km(1, 2) allotypes in an IgG1 (__K__) human myeloma protein (protein LEC). Heavy and light chains spontaneously dissociate in sodium dodecyl sulfate polyacrylamide gels. Light chains appear to be covalently