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Human hepatoma cells synthesize and secrete insulin-like growth factor Ia prohormone under growth hormone control

✍ Scribed by C.A. Conover; B.K. Baker; L.K. Bale; J.T. Clarkson; F. Liu; R.L. Hintz


Book ID
119118082
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
612 KB
Volume
48
Category
Article
ISSN
0167-0115

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Monkey retinal pigment epithelial cells
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## Abstract Cultured monkey retinal pigment epithelial (RPE) cells rapidly secrete large amounts of insulin‐like growth factor binding proteins (IGF‐BPs). IGF‐II tracer binding activity in conditioned media is two to three times greater than that of IGF‐I. Under reducing SDS‐PAGE conditions, ^125^I