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Human hand function: the limitations of brain and brawn

✍ Scribed by Simon C. Gandevia; Richard C. Fitzpatrick

Book ID
110117859
Publisher
Cambridge University Press
Year
2011
Tongue
English
Weight
445 KB
Volume
589
Category
Article
ISSN
0022-3751

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Plectin is a 580 kDa intracellular protein, previously shown to link intermediate filaments with microtubules, actin filaments, and membrane components. Disruption of the plectin gene in humans and in mice results in severe skin blistering and muscular degeneration, consistent with plectin's structu