Gene therapy: Advances and limitations
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Ascher, Nancy L.
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Article
📅
1996
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Wiley (John Wiley & Sons)
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English
⚖ 148 KB
Recombinant adenovirus vectors are efficient at transferring genes into somatic tissues but are limited for use in clinical gene therapy by immunologic factors that result in the rapid loss of gene expression and inhibit secondary gene transfer. This study demonstrates that systemic coadministration