Human gene targeting by viral vectors
โ Scribed by Russell, David W.; Hirata, Roll K.
- Book ID
- 109915777
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 711 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1061-4036
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In a review article Miller [1] reported on the state of the art of human gene therapy as it was summarized in a meeting at the end of December 1991. The human trials in which human genes were successfully transferred in vitro to mark cells of patients and for gene therapy of genetic disorders. The a
Retroviral vectors have been widely studied as vehicles for hepatocyte gene therapy, but they are limited by an inability to infect nondividing cells and the need for prolonged cell culture. Two replication deficient herpes simplex viral vectors (HSV) were constructed with the marker genes Zac-Z//%g