Based on the analysis of the drafts of the human genome sequence, it is being speculated that our species may possess an unexpectedly low number of genes. The quality of the drafts, the impossibility of accurate gene prediction and the lack of sufficient transcript sequence data, however, render suc
Human gene discovery through experimental definition of transcribed regions of the human genome
β Scribed by Anamaria A Camargo; Sandro J de Souza; Ricardo R Brentani; Andrew J.G Simpson
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 48 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1367-5931
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We have undertaken a systematic study of primary human breast tumor DNA to identify and characterize frequently occurring somatic mutations. Loss of heterozygosity (LOH) has been the most frequent mutation in our panels of primary breast tumor DNA. It is currently thought that LOH reveals recessive
In the past few years the number of copy number variants (CNVs) identified in the human genome has increased significantly, but our understanding of the functional impact of CNVs is still limited. Clinically significant variations cannot easily be distinguished from benign, complicating interpretati