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Human fetal schwann cells in culture: Phenotypic expressions and proliferative capabibility

✍ Scribed by S. U. Kim; V. W. Yong; K. Watabe; D. H. Shin

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 1014 KB
Volume: 22
Category: Article
ISSN: 0360-4012
DOI: 10.1002/jnr.490220107

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✦ Synopsis

In this report we examined the phenotypic expressions and the proliferative capability of cultured human fetal Schwann cells. Antigens that were expressed included laminin, nerve growth factor receptor, neural cell adhesion molecule, S-100 protein, and that recognized by the monoclonal antibody HNK-1. In addition, HLA-A,B,C and HLA-DR, respectively, class I and class 11 antigens of the major histocompatibility complex, were demonstrated on Schwann cells. Mitotic capability was high, with an average of 34% of Schwann cells undergoing proliferation over a 2-day period.

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