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Human fetal retinal pigment epithelium suppresses the activation of CD4+and CD8+T-cells

✍ Scribed by L. Farrokh-Siar; K. A. Rezai; R. T. Semnani; S. C. Patel; J. T. Ernest; G.A. van Seventer


Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
87 KB
Volume
237
Category
Article
ISSN
0065-6100

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CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta