Human Fallopian Tube Mesenchymal Stromal Cells Enhance Bone Regeneration in a Xenotransplanted Model
✍ Scribed by Tatiana Jazedje, Daniela F. Bueno, Bruno V. P. Almada, Heloisa Caetano, Carlos E. Czeresnia, Paulo M. Perin, Silvio Halpern, Mariangela Maluf, Lucila P. Evangelista, Marcelo G. Nisenbaum, Marília T. Martins, Maria R. Passos-Bueno, Mayana Zatz
- Book ID
- 113093075
- Publisher
- Humana Press Inc
- Year
- 2011
- Tongue
- English
- Weight
- 702 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1550-8943
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Mesenchymal stem cells (MSCs) were demonstrated to exist within peripheral blood (PB) of several mammalian species including human, guinea pig, mice, rat, and rabbit. Whether or not the PB derived MSCs (PBMSCs) could enhance the regeneration of large bone defects have not been reported. In this stud
## Abstract We hypothesized that bone morphogenetic protein‐2 (BMP‐2) would significantly enhance __in vivo__ bone formation efficacy of osteogenically undifferentiated human cord blood mesenchymal stem cells (hCBMSCs). To test this hypothesis, poly(lactic‐__co__‐glycolic acid)/hydroxyapatite (PLGA