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Human ex vivo carcinoma cells produce transforming growth factor β and thereby can inhibit lymphocyte functions in vitro

✍ Scribed by F. Vánky; Noémi Nagy; Christina Hising; Kerstin Sjövall; Barbro Larson; Eva Klein

Book ID
105968175
Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
390 KB
Volume
43
Category
Article
ISSN
0340-7004

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## Abstract The effects of EGF and TGF‐β1 on the proliferation of 2 ovarian carcinoma cell lines (IGROV1 and OVCCR1) were evaluated. The cell lines were adapted to grow in a restricted serum (0.5%) medium. EGF was required for proliferation of both ovarian cell lines. Low doses of TGF‐β1 inhibited