Human erythrocyte glutathione s-transferase: A possible marker of chemical exposure
β Scribed by Ansari, G.A.S.; Singh, Shivendra V.; Gan, Jose C.; Awasthi, Y.C.
- Book ID
- 122390483
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 367 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0378-4274
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Trivalent antimony (SB β«3β¬ ) in the form of potassium antimony tartrate was found to be an inhibitor of glutathione-S-transferases (GST) from human erythrocytes with a 50% inhibition concentration (IC 50 ) of 0.05 mM. The inhibition was, however, incomplete with 15-20% of the GST activity remaining
Glutathione 5'-transferases: Two-dimensional electrophoretic protein markers of lead exposure Glutathione S-transferases (GST) are a family of detoxification isoenzymes that catalyze the conjugation of xenobiotics and their metabolites with reduced glutathione. Lead exposure in rats is known to indu