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Human endonuclease V as a repair enzyme for DNA deamination

✍ Scribed by Rongjuan Mi; Maria Alford-Zappala; Yoke W. Kow; Richard P. Cunningham; Weiguo Cao


Book ID
113809660
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
896 KB
Volume
735
Category
Article
ISSN
0027-5107

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## Abstract The feasibility of detection of carcinogenic chemicals using DNA repair synthesis of cultured human fibroblasts as measured by an unscheduled ^3^HTdR incorporation has been explored. Of 64 chemicals tested, 29 were proximate or ultimate carcinogens, 15 were precarcinogens that required