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Human embryonic stem cells derived without feeder cells

✍ Scribed by Irina Klimanskaya; Young Chung; Lorraine Meisner; Julie Johnson; Michael D West; Robert Lanza

Book ID: 117289421
Publisher: The Lancet
Year: 2005
Tongue: English
Weight: 950 KB
Volume: 365
Category: Article
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(05)66473-2

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## Abstract The majority of human embryonic stem cell lines depend on a feeder cell layer for continuous growth in vitro, so that they can remain in an undifferentiated state. Limited knowledge is available concerning the molecular mechanisms that underlie the capacity of feeder cells to support bo