Human Dopamine D3 and D2L Receptors Couple to Inward Rectifier Potassium Channels in Mammalian Cell Lines
β Scribed by Eldo V. Kuzhikandathil; Weifeng Yu; Gerry S. Oxford
- Book ID
- 115637545
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 370 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1044-7431
No coin nor oath required. For personal study only.
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We utilized the approach of stably expressing different dopamine (DA) receptors into identified cell lines in an attempt to better understand the coupling of these receptors to membrane ion channels via second messenger systems. Recently, we examined the N18TG2 x mesencephalon (MES-23.5) cell line t
The D2-like dopamine (DA) receptor family has continued to expand and now includes the D2-short (Das) and Dz-long (D2,,) receptor isoforms and the D3 and D4 receptors. The D2 receptor isoforms differ in length by 29 amino acids within the third cytoplasmic loop, a region of the receptor believed to