✦ LIBER ✦

Human DNA ligase I completely encircles and partially unwinds nicked DNA

✍ Scribed by Pascal, John M.; O'Brien, Patrick J.; Tomkinson, Alan E.; Ellenberger, Tom

Book ID: 109893412
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 430 KB
Volume: 432
Category: Article
ISSN: 0028-0836
DOI: 10.1038/nature03082

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Human DNA ligase I efficiently seals nic

Human DNA ligase I efficiently seals nicks in nucleosomes

✍ Chafin, D. R. 📂 Article 📅 2000 🏛 Nature Publishing Group 🌐 English ⚖ 552 KB

The DNA binding domain of human DNA liga

The DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, PCNA and hRad9-hRad1-hHus1

✍ Wei Song; John M. Pascal; Tom Ellenberger; Alan E. Tomkinson 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 667 KB

Human DNA Ligase IV and the Ligase IV/XR

Human DNA Ligase IV and the Ligase IV/XRCC4 Complex: Analysis of Nick Ligation Fidelity †

✍ Wang, Yu; Lamarche, Brandon J.; Tsai, Ming-Daw 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 378 KB

Distinct kinetics of human DNA ligases I

Distinct kinetics of human DNA ligases I, IIIα, IIIβ, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair

✍ Xi Chen; Jeff D. Ballin; Julie Della-Maria; Miaw-Sheue Tsai; Elizabeth J. White; 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 709 KB

Inhibition of human DNA ligase I activit

Inhibition of human DNA ligase I activity by zinc and cadmium and the fidelity of ligation

✍ Shu Wei Yang; Frederick F. Becker; John Y. H. Chan 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 650 KB

Heavy metals, including zinc (Zn) and cadmium (Cd), are potentially important genotoxic agents in our environment. Here we report that human DNA ligase I, the major form of the enzyme in replicative cells, is a target for Zn and Cd ions. ZnCl2 at 0.8 mM caused complete inhibition of DNA ligase I act

Comparison of responses of DNA topoisome

Comparison of responses of DNA topoisomerase I from Candida albicans and human cells to four new agents which stimulate topoisomerase-dependent DNA nicking

✍ J Fostel; D Montgomery; P Lartey 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 614 KB