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Human Cytomegalovirus-Mediated Induction of MIF in Fibroblasts

✍ Scribed by Michael Bacher; Markus Eickmann; Joerg Schrader; Diethard Gemsa; Andreas Heiske

Book ID
112274072
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
567 KB
Volume
299
Category
Article
ISSN
0042-6822

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Because of the unique interdependence of human cytomegalovirus (HCMV) and the physiological state of the host cell, we evaluated the ability of human foreskin fibroblasts (HFF), exposed to gamma radiation, to support HCMV growth. Irradiation of HFF with 2,500 rADS prevented cellular proliferation an