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Human cytomegalovirus (HCMV) replication kinetics in stem cell transplant recipients following anti-HCMV therapy

✍ Scribed by Hubertus C.E. Buyck; Paul D. Griffiths; Vincent C. Emery


Book ID
116631916
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
178 KB
Volume
49
Category
Article
ISSN
1386-6532

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The kinetics of the gB-specific and neutralizing antibody responses to human cytomegalovirus (HCMV) were analyzed in 26 allogeneic stem-cell transplant recipients who either did (n = 20) or did not (n = 6) develop asymptomatic HCMV active infection during the study period. Antibody response profiles

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## Abstract Transplantation Centers using human cytomegalovirus (HCMV) antigenemia‐based preemptive therapy will need to replace in the near future the antigenemia assay with a more standardized and automatable assay, such as a molecular assay quantifying HCMV DNA in blood (DNAemia). Thus, in view