Human Cytogenetic Cancer Markers provides state-of-the-art reviews of both basic research and clinical applications of the chromosomal markers of cancer. These new markers offer great promise, not only for their clinical utility in diagnosis, prognosis, and disease monitoring, but also for their contributions to a better understanding of the mechanisms of tumor development and progression. The contributors-all leading researchers and practitioners in the field-insightfully reveal fresh insights into the translational role of cytogenetics in identifying the cellular and molecular changes that occur in cancer. Coverage is devoted to many tissue systems-colon, breast, prostate, lung, skin, brain, and kidney-where the diagnostic and prognostic utility of chromosome markers is clearly demonstrated.
Human Cytogenetic Cancer Markers describes the emerging utility of molecular markers in the precise and specific definition of tumors and their behavior, thus establishing these genetic markers as the most accurate means to diagnose cancer and predict its course. Wolman and Sell have produced a seminal book certain to become the front-line reference and authoritative resource needed by all scientists and clinicians engaged in cancer research, diagnosis, and management.