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Human complement C4 locus is duplicated on some chromosomes

✍ Scribed by OLAISEN, BJØRNAR; TEISBERG, PER; NORDHAGEN, RANNVEIG; MICHAELSEN, TERJE; GEDDE-DAHL, TOBIAS


Book ID
109714344
Publisher
Nature Publishing Group
Year
1979
Tongue
English
Weight
332 KB
Volume
279
Category
Article
ISSN
0028-0836

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Gene responsible for dificient activity
✍ Shinobu Tanaka; Takakazu Suzuki; Mitsuru Sakaizumi; Yoshinobu Harada; Yoshibumi 📂 Article 📅 1991 🏛 Springer-Verlag 🌐 English ⚖ 530 KB

Sera from 73 strains of mice were tested for hemolytic activity through the classical and the alternative pathways (CP and AP) in a single radial hemolysis assay. Sera from 16 out of 45 laboratory inbred strains had no lytic activity, and Ouchterlony analysis with anti-C5 serum showed them to be C5-