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Human cellular prion protein interacts directly with clusterin protein

โœ Scribed by Fei Xu; Elena Karnaukhova; Jaroslav G Vostal


Book ID
116270677
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
445 KB
Volume
1782
Category
Article
ISSN
0925-4439

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A fragment of the prion protein (PrP106-126) induces cell death in cultures of wild-type embryonic day (E)16 mouse cortical neurons but not cells derived from mice devoid of cellular PrP(PrP o/o) . Two common binding partners for PrP106-126 expressed in both wild-type and PrP o/o mouse brain were is