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Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

✍ Scribed by Draetta, Giulio; Piwnica-Worms, Helen; Morrison, Deborah; Druker, Brian; Roberts, Thomas; Beach, David

Book ID
109757421
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
892 KB
Volume
336
Category
Article
ISSN
0028-0836

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## Abstract The protein kinase CK2 is constituted by two catalytic (Ξ± and/or Ξ±β€²) and two regulatory (Ξ²) subunits. CK2 phosphorylates more than 300 proteins with important functions in the cell cycle. This study has looked at the relation between CK2 and p27^KIP1^, which is a regulator of the cell c