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Human CC chemokine CCL23 enhances expression of matrix metalloproteinase-2 and invasion of vascular endothelial cells

✍ Scribed by Kyung-No Son; Jungsu Hwang; Byoung S. Kwon; Jiyoung Kim


Book ID
116292017
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
345 KB
Volume
340
Category
Article
ISSN
0006-291X

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## Abstract Matrix metalloproteinase‐13 (MMP‐13) is involved in the degradation of extracellular matrix in many kinds of tissues. Here we found that hypoxia increased MMP‐13 protein and mRNA levels in primary rat astrocyte cultures. Hypoxia stimulation also increased the secretion of MMP‐13 from as