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Human cancer: etiologic agents/dose responses/DNA repair/cellular and animal models

โœ Scribed by Richard B Setlow


Book ID
114070357
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
72 KB
Volume
477
Category
Article
ISSN
0027-5107

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โœ Edelmann, Lisa ;Edelmann, Winfried ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 143 KB ๐Ÿ‘ 2 views

## Abstract Germline mutations in DNA mismatch repair genes underlie one of the most common hereditary cancer predisposition syndromes known in humans, hereditary nonpolyposis colorectal cancer (HNPCC). Defects of the DNA mismatch repair system are also prevalent in sporadic colorectal cancers. The