Human C7 polymorphism: Quantitative analysis of different phenotypes
β Scribed by Keiko Washio; Katsushi Tokunaga; George Dewald; Shogo Misawa; Keiichi Omoto
- Publisher
- Nature Publishing Group
- Year
- 1988
- Tongue
- English
- Weight
- 506 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1435-232X
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A C7 cDNA probe detecting a TaqI restriction fragment length polymorphism has been used to examine the segregation of the "silent allele" (C7\*Q0) in two familial deficiencies. Carrier diagnosis in healthy children is possible when both parents are heterozygotes. Only one of these two families was i
We analyzed two quantitative traits (QI and Q2) provided in the 'Common Disease' data set with the aim of detecting both genetic and environmental determinants. We used linear regression for screening measured variables, maximum likelihood segregation and linkage analyses for detecting and localizin